2025
Montarolo F, Gao F, Loddo M, Milek J, Zawadzka M, Miniaci MC, Brusco A, Balbo I, Dziembowska M, Tempia F, Skowronska-Krawczyk D, Hoxha E. (2025) Impact of Elovl5 Deficiency on Cerebellar Excitatory Synaptic Transmission in Mice. Journal of Neuroscience. Sep 17;45(38):e1529242025. doi: 10.1523/JNEUROSCI.1529-24.2025.
Scaramuzza L*, Ribodino M*, Cassarino C§, Morrocchi M§, Gomez Gonzalez GB§, Parolisi R§, Sozzi E, Turrini G, Cerrato V, Conforti P, Hoxha E, Tognato R, Galeotti G, Cordiglieri C, Crosti MC, Zucca S, Lorenzati M, Bovetti S, Spaiardi P, de’Sperati C, Biella G, Ottoboni L, Parmar M, Maestri S, Besusso D, Cattaneo E, Buffo A. Transplanted human striatal progenitors exhibit functional integration and modulate host circuitry in a Huntington’s disease animal model. Pharmacol Res. 2025 219:107905. doi: 10.1016/j.phrs.2025.107905. (* co-first authors; § co-second authors)
Cerrato V, Turrini G, Vitali I, Xiong B, Solanelles-Farré L, Lopes, A Magrinelli E, Bocchi R, Götz M, Fischer-Sternjak J, Boda E, Buffo A*, Telley L* A single-cell transcriptomic atlas maps cerebellar astrocyte diversity and uncovers the transcriptional code underlying their maturation trajectories. Preprint bioRXiv 2025.07.17.665323 https://doi.org/10.1101/2025.07.17.665323 (* co-last authors)
Morellato A§, De Gregorio M§, Angelini C§, Torelli F, Belmonte V, Alfieri A, Bersia B, Cravero T, Gai M, Bianciotto OT, Oddone R, Salemme V, Natalini D, Centonze G, Nigrelli F, Raspanti A, Gurgone A, D’Attanasio G, Mele P, Eva C, Lodi A, Gavello D, Carabelli V, Hidisoglu E, Chiantia G, Carbone E, Becchetti A, Giustetto M, Marcantoni A, Turco E, Bertocchi I*, Defilippi P* (2025). The adaptor protein SKT interacts with PSD-95 and SHANK3 and affects synaptic functions. Cell Reports, 44, 116206, September 23, 2025. IF 6.9
Pattaro A, Ghibaudi M, Corrente C, Telitsyn N, Graic J-M, Aresu L, Sherwood CC, Bonfanti L. Phylogenetic variation of layer II cortical immature neurons in dog and horse confirms covariance with brain size and neocortical surface. Brain Structure &Function 2025.
Ghibaudi M, La Rosa C, Telitsyn N, Graїc J-M, Faulkes CG, Sherwood CC, Bonfanti L. Multispecies characterization of immature neurons in the mammalian amygdala reveals their expansion in primates. Plos Biology 2025.
Bonato M*, Cerrato V*, Dioni L, Montarolo F, Parolisi R, Bertolotto A, Bollati V, Ferrari L, Boda E (2025). Short-term exposure to particulate matter triggers a selective alteration of plasma extracellular vesicle-packaged miRNAs in a mouse model of Multiple Sclerosis. (*co-first). Front Immunol 16, doi:10.3389/fimmu.2025.1596935
Bocchi R, Thorwirth M, Simon-Ebert T, Koupourtidou C, Clavreul S, Kolf K, Della Vecchia P, Bottes S, Jessberger S, Zhou J, Wani G, Pilz GA, Ninkovic J, Buffo A, Sirko S, Götz M, Fischer-Sternjak J (2025) Astrocyt eheterogeneity reveals region-specific astrogenesis in the white matter. Nat Neurosci. 28(3):457-469. doi: 10.1038/s41593-025-01878-6
Garello F, Cavallari E, Capozza M, Ribodino M, Parolisi R, Buffo A, Terreno E. (2025) MRI detection of free-contrast agent nanoparticles.MagnReson Med. 93(2):761-774. doi: 10.1002/mrm.30292.
Iegiani G, Pallavicini G, Pezzotta A, Brix A, Ferraro A, Gai M, Boda E, Bielas SL, Pistocchi A, Di Cunto F.(2025) CITK modulates BRCA1 recruitment at DNA double strand breaks sites through HDAC6.Cell Death Dis. 16(1):320. doi: 10.1038/s41419-025-07655-4.PMID: 40254670
Ghibaudi M, Boda E, Bonfanti L. (2025) From mice to humans: a need for comparable results in mammalian neuroplasticity. Neural Regen Res. 20(2):464-466. doi: 10.4103/NRR.NRR-D-24-00143.
Bonato M, Montarolo F, Parolisi R, De Francia S, Pandino C, Di Cintio N, Bertolotto A, Buffo A, Boda E (2025) Acute particulate matter (PM10) exposure selectively triggers behavioral alterations in the presymptomatic Experimental Autoimmune Encephalomyelitis (EAE) mouse model of Multiple Sclerosis preprint bioRXivdoi.org/10.1101/2025.03.20.644303
Ghibaudi M, Zanone A, Bonfanti L. Brain structural plasticity in large-brained mammals:not only narrowing roads. Neural Regeneration Research 2025. doi:10.4103/NRR.NRR-D-24-01438.
Chiappini V, Castillo MFV, Biancardi F, Di Cunto F, Magistretti PJ, Vercelli A, Agus M, Calì C. (2025) Ultrastructure of astrocytes using volume electron microscopy: A scoping review. J Physiol. 2025 Mar 3. doi: 10.1113/JP287455
Bartesaghi L, Giangreco B, Chiappini V, Veloz Castillo MF, Monaco M, Médard, J.-J, Gambarotta G, Agus M, Calì C (2025). Tight Spaces, Tighter Signals: Spatial Constraints as Drivers of Peripheral Myelination. Cells. 14, 926.doi: 10.3390/cells14120926.
Calì C, Wang X (2025). Editorial: Advances in volume electron microscopy for brain imaging: methods, applications, and affordability. Front. Neurosci. 19:1561852. doi: 10.3389/fnins.2025.1561852.
Cangelosi A, Riberi G, Titolo P, Salvi M, Molinari F, Ulrich L, Vezzetti E, Agus M, Calì C (2025). Augmented reality simulation framework for minimally invasive orthopedic surgery. ComputBiol Med. 189:109943. doi: 10.1016/j.compbiomed.2025.109943.
Dallere S, Rasà DM, Pavarino G, Schellino R, Vercelli A, Boido M (2025). The exposome from neurodevelopment to neurodegeneration: a narrative review. NeurosciBiobehav Rev. 106247. doi: 10.1016/j.neubiorev.2025.106247.
Lombardi I, Ferrero C, Vulcano E, Rasà DM, Gelati M, Pastor D, Carletti RM, de la Morena S, Profico DC, Longobardi S, Lazzarino E, Perciballi E, Rosati JD, Martinez S, Vercelli A, Vescovi AL, Boido M, Ferrari D (2025). Safety and efficacy evaluation of intracerebroventricular human neural stem cell transplantation in SOD1 mice as a novel approach for ALS. J Transl Med. 23(1):529. doi: 10.1186/s12967-025-06529-9.
Madeira R, Esteves D, Pinto N, Vercelli A, Vaz Patto M (2025). Acceptance Factors and Barriers to the Implementation of a Digital Intervention With Older Adults With Dementia or Caregivers: Protocol for an Umbrella Review. JMIR Res Protoc. 14:e56584. doi: 10.2196/56584.
Rasà DM, Stoppa I, Bérenger-Currias N, Pasho E, Ciura S, Kabashi E, Martinat C, Boido M (2025). Stress exposure affects amyotrophic lateral sclerosis pathogenesis via PI3K/Akt and focal adhesion pathways: evidence from three experimental models. Sci Rep. 21;15(1):17583. doi: 10.1038/s41598-025-02167-9.
Riberi G, Cangelosi A, Titolo P, Dutto E, Salvi M, Molinari F, Ulrich L, Agus M, Calì C (2025). Validation Study on Iatrogenic Nerve Damage Reduction Using Augmented Reality on Elbow Phantom. Mayo ClinProc Digit Health. 3(2):100221. doi: 10.1016/j.mcpdig.2025.100221.
Rother F,Parmar AR, Bodenhagen JS, Marvaldi L, Hartmann E, Bader M (2025). Deficiency in KPNA4, but Not in KPNA3, Causes Attention Deficit/Hyperactivity Disorder like Symptoms in Mice. Genes. 16,190. doi:10.3390/genes16060690.
Shah U, Agus M, Boges D, Aldous V, Chiappini V, Alzubaidi M, Hadwiger M, Magistretti PJ, Househ M, Calí C (2025). AI-guided immersive exploration of brain ultrastructure for collaborative analysis and education. Comput Graph. 129, Article 104239. doi: 10.1016/j.cag.2025.104239.
Lado W, Wu X, Choi S, Dong Y, Yang G, Arancio O, Tempia F, Miniaci MC, Sulzer D, Mosharov E, Tang G (2025) Synaptic plasticity deficits in a mouse model of Timothy syndrome: LTP saturation and its pharmacological rescue by nifedipine. Biomed Pharmacother. 2025 Feb 11;184:117896. doi: 10.1016/j.biopha.2025.117896.
Montarolo F, Thielens S, Bove M, Bertolotto A, Tempia F, Hoxha E. (2025) NURR1 deficiency is associated to altered microglial phenotype in male mice. Mol Neurobiol. 2025 Mar 8. doi: 10.1007/s12035-025-04787-8.
Francesca Montarolo, Anita Maria Rominto, Luna Berrino, Antonio Bertolotto, Fernanda Laezza, Filippo Tempia, Eriola Hoxha (2025) Deletion of Fgf14 confers resilience to basal and stress-induced depressive-like behavior and reduces anxiety in mice. Transl Psychiatry 15(1):136. doi: 10.1038/s41398-025-03361-z.
Novi G, Bovis F, Sciolla C, Frau J, Minetti M, Napoli F, Vianello M, Greco G, Sechi E, Bellomo A, Garelli P, Spiezia AL, Fantozzi R, Schirò G, Ghezzi L, Zecca C, Signoriello E, Brambilla L, Lucchini M, Bonavita S, Schiavetti I, Malentacchi M, Cocco E, Franceschini A, Mataluni G, Gastaldi M, Rolando A, Solla P, Cellerino M, Abbadessa G, Lanzillo R, Di Sapio A, Uccelli A, Sormani MP. (2025). Long-Term Effectiveness and Safety of Rituximab in Neuromyelitis Optica Spectrum Disorder: A 5-Year Observational Study. CNS drugs, 10.1007/s40263-025-01191-7. Advance online publication. https://doi.org/10.1007/s40263-025-01191-7
Malucchi, S., Perini, P., Rinaldi, F., Radaelli, M., Malentacchi, M., Bertolotto, A., & Di Sapio, A. (2025). Disease Course in Patients Switched from Natalizumab to Alemtuzumab: An Italian Multicenter, Prospective, Observational Study. Neurology and therapy, 10.1007/s40120-025-00754-6. Advance online publication. https://doi.org/10.1007/s40120-025-00754-6
Centonze, D., Di Sapio, A., Brescia Morra, V., Colombo, E., Inglese, M., Paolicelli, D., Salvetti, M., & Furlan, R. (2025). Steps toward the implementation of neurofilaments in multiple sclerosis: patient profiles to be prioritized in clinical practice. Frontiers in neurology, 16, 1571605. https://doi.org/10.3389/fneur.2025.1571605
Mechelli R, Umeton R, Bellucci G, Bigi R, Rinaldi V, Angelini DF, Guerrera G, Pignalosa FC, Ilari S, Patrone M, Srinivasan S, Cerono G, Romano S, Buscarinu MC, Martire S, Malucchi S, Landi D, Lorefice L, Pizzolato Umeton R, Anastasiadou E, Trivedi P, Fornasiero A, Ferraldeschi M; IMSGC WTCCC2; Di Sapio A, Marfia G, Cocco E, Centonze D, Uccelli A, Di Silvestre D, Mauri P, de Candia P, D’Alfonso S, Battistini L, Farina C, Magliozzi R, Reynolds R, Baranzini SE, Matarese G, Salvetti M, Ristori G. (2025). A disease-specific convergence of host and Epstein-Barr virus genetics in multiple sclerosis. Proceedings of the National Academy of Sciences of the United States of America, 122(14), e2418783122. https://doi.org/10.1073/pnas.2418783122
Giatti S, Gotti S, Melcangi RC. (2025) Steroids and nervous system-2024. J Neuroendocrinol. 2025 May 21:e70048. doi: 10.1111/jne.70048.
Bonaldo B, Casile A, Bettarelli M, Marraudino M, Gotti S (2025)Perinatal exposure to bisphenol A or S alters differently sexual behavior and kisspeptin system in mice. Environ Res. Mar 15;269:120888. doi: 10.1016/j.envres.2025.120888.
Marraudino M, Nasini S, Porte C, Bonaldo B, Macchi E, Ponti G, Keller M, Gotti S (2025) Infant mice fed soy-based formulas exhibit alterations in anxiety-like behaviours and the 5-HT system.Toxicology. Feb;511:154035. doi: 10.1016/j.tox.2024.154035.
Casile A, Marraudino M, Bonaldo B, Micioni Di Bonaventura MV, Nasini S, Cifani C, Gotti S (2025) Novel rat model of gaming disorder: assessment of social reward and sex differences in behavior and c-Fos brain activity. Psychopharmacology (Berl). May;242(5):1103-1122. doi: 10.1007/s00213-024-06576-y.
Quarta E, Bourqqia-Ramzi M, Muñoz-Rodriguez D, García-Esteban MT, Murciano-Cespedosa A, Mateos González Á, Conejero-Meca FJ, Lombardo-Hernandez J, Mansilla-Guardiola J, Baroni S, GeninattiCrich S, Geuna S, Munaron L, Chiabrando D, Herrera-Rincon C. (2025) Impact of Iron Deficiency on the Growth and Bioelectrical Profile of Different Gut Bacteria. Microbiologyopen.14(3):e70015. doi: 10.1002/mbo3.70015.
Önger ME, Geuna S, Elhaj AE, Raimondo S, Kaplan S. (2025) Regeneration responses of Ankaferd Blood Stopper, platelet-rich-plasma, and Momordica charantia on sciatic nerve injury in the obese rats. Biomed Mater.20(4). doi: 10.1088/1748-605X/add97c.
Alvites R, Lopes B, Coelho A, Sousa AC, Sousa P, Moreira A, Rêma A, Simões M, Mendonça C, Atayde L, Prada J, Pires I, Silva B, João F, Metafune M, Bertone F, Raimondo S, Alves N, Luís AL, Maurício AC. (2025) Combined use of olfactory mucosal mesenchymal stem cells conditioned medium and neural guide conduits promotes nerve regeneration in an ovine model. Front Cell Dev Biol.13:1598736.
doi: 10.3389/fcell.2025.1598736.
García-Bejarano M, Aucello R, Zen F, El Soury M, Cordero F, de la Fuente JM, Perroteau I, Ronchi G, Gambarotta G.(2025) Dynamic regulation of Rgs16 and its correlation with Neuregulin1 expression in acute and chronic nerve injury. Front Cell Dev Biol.13:1540453. doi: 10.3389/fcell.2025.1540453.
Fregnan F, Muratori L, Crosio A, Zen F, Fiori C, Tonazzini I, Gambarotta G, Martinelli A, Meziere J, Raimondo S, Manfredi M, Scaccini L, Geuna S, Porpiglia F.(2025) A novel rat model for studying bilateral cavernous nerve damage in vivo: exploring the potential of chitosan-blended membranes for nerve regeneration post-radical prostatectomy. Minerva UrolNephrol. 77(1):91-110. doi: 10.23736/S2724-6051.25.06169-5.
Ronchi G, Pellegrino D, El Soury M, Amato O, Gaia F, Farzin S, Nuzzi R, Basic M, Bolsega S, Geuna S,Cescon M, Haastert-Talini K, Gambarotta G.(2025) Gut microbiota regulates optic nerve fiber myelination. Front Cell Dev Biol.13:1526855. doi: 10.3389/fcell.2025.1526855.
Aucello R, Pernice S, Tortarolo D, Calogero RA, Herrera-Rincon C, Ronchi G, Geuna S, Cordero F, Lió P, Beccuti M. (2025) Unified Great Mod: a new holistic modelling paradigm for studying biological systems on a complete and harmonious scale. Bioinformatics. 41(3):btaf103. doi: 10.1093/bioinformatics/btaf103.
Ronchi G, Cescon M, Gambarotta G, Haastert-Talini K. (2025) Peripheral nervous system and gut microbiota: emerging evidence on increased mechanistic understanding to reveal innovative strategies for peripheral nerve regeneration. Neural Regen Res. doi: 10.4103/NRR.NRR-D-24-01310.
Ronchi G, Ackva C, Fregnan F, Zen F, Muratori L, Crosio A, Metzen J, Haastert-Talini K. (2025) Chitosan-Based Materials for Peripheral Nerve Repair-New Pre-Clinical Data on Degradation Behavior at the Nerve Repair Site and Critical Opinion on Their Translational Impact. Int J Mol Sci.26(3):1214. doi: 10.3390/ijms26031214.
Lopes B, Sousa AC, Sousa P, de Sousa Moreira A, Coelho AF, Atayde L, Salgado AJ, Geuna S, Alvites R, Maurício AC. (2025) In vitro evaluation of dental pulp stem cells for sciatic nerve regeneration: foundations for future in vivo applications. Front Cell Dev Biol.13:1528213. doi: 10.3389/fcell.2025.1528213.
Mahmoudian M, Trotta F, Raimondo S, Bussolino F, Arese M.(2025) Cell Membrane-Integrated Neuroligin-1 Regulates the Anti-Inflammatory Effects of CRC Cell-Derived Exosomes. Int J Mol Sci. 26(2):503. doi: 10.3390/ijms26020503.