Partnership

Prof. Stephanie Bielas , Department of Human Genetics, University of Michigan Medical School, Ann Arbor, Michigan, USA
Dissection of common mechanisms in genetic primary microcephaly | – Project PRIN 2022- Next Generation EU program
PI NICO Prof. Ferdinando Di Cunto

Prof. Bielas contributes to the project by providing her expertise in the field of human genetics, as well as patient-derived iPSC cells and human brain organoids produced from them.

Prof. Laura Ciapponi (University) and Dr. Maria Patrizia Somma (CNR)
Department of Biology and Biotechnology, Sapienza University of Rome, Italy.
Dissection of common mechanisms in genetic primary microcephaly | Project PRIN 2022- Next Generation EU program
PI NICO Prof. Ferdinando Di Cunto

The collaborators participate to the project through their outstanding expertise with the usage of Drosophila models for the studi of genes involved in cell division cycle and DNA damage repair.

Prof. Shaun Stauffer, Center for Therapeutics Discovery, Lerner Research Institute, Cleveland Clinic, Cleveland, Ohio, United States.
Development of Citron Kinase as a therapeutic target for brain tumors | Italian Association for Cancer Research (AIRC)
PI NICO Prof. Ferdinando Di Cunto

The collaboration involves the exchange of the CITK inhibitory compounds identified and characterized by the two groups.

Prof. Roberta Rudà, Division of Neuro-Oncology, Department of Neuroscience “Rita Levi Montalcini”, University of Turin, Italy.

Dr. Ciro Mercurio, IFOM ETS – The AIRC Institute of Molecular Oncology (Experimental Therapeutics Program), Milan, Italy.

Related News

Modeling primary microcephaly with human brain organoids reveals fundamental roles of CIT kinase activity

Journal of Clinical Investigations, September 2024. Brain organoids: an ideal model for studying human microcephalies.

Small worm, big impact: Nobel prize for Ambros’s and Ruvkun’s microRNAs

The 2024 Nobel Prize in Medicine goes to Ambros and Ruvkun for the discovery of microRNAs. A breakthrough that began with basic research on a tiny worm, now crucial for gene regulation.

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