Research News

Plos Biology, August 2025 Marco Ghibaudi 1 2, Chiara La Rosa 1, Nikita Telitsyn 1 2, Jean-Marie Graїc 3, Chris G Faulkes 4, Chet C Sherwood 5, Luca Bonfanti 1�

Our study shows dramatic change in length and level of unsaturation of lipids in synaptosomes isolated from Elovl5 knock-out mice. These results suggest that the shift in PU

Cell Reports, September 2025 Highlights • SKT is a postsynaptic scaffold interacting directly with PSD95 and SHANK3 • SKT loss causes defects in dendritic spine forma

Global Day ALS - Our Brain Development and Disease group recently published two articles that help clarifying some of its causes and suggest new therapeutic options.

Journal of Clinical Investigations, September 2024. Brain organoids: an ideal model for studying human microcephalies.

The 2024 Nobel Prize in Medicine goes to Ambros and Ruvkun for the discovery of microRNAs. A breakthrough that began with basic research on a tiny worm, now crucial for gene r

Alzheimer’s, the most common neurodegenerative disease, begins affecting the brain decades before symptoms appear, with serious impacts on patients, families, and society.

The study, the result of a collaboration between NICO, the University of Turin, Padua, and Hannover, opens new therapeutic perspectives for nerve injuries.

Luca Bonfanti proposes a novel evolutionary trade-off between adult neurogenesis and the presence of immature neurons—two processes that coexist with varying significance ac

Our researchers explore new in vitro models based on tissue engineering in their review published in Frontiers in Medical Engineering.

Our researchers, in collaboration with Pharmafox, have patented ActR-Fc-nLG3, a molecule that strengthens muscles and neuromuscular junctions.

A study by NICO shows that transplanting neurons derived from human embryonic stem cells could offer new therapeutic hope for Huntington’s disease.

The NICO study identifies Lestaurtinib as a promising candidate for medulloblastoma treatment, thanks to its potential for drug repurposing.

Research by NICO and the Sleep Center of Turin shows that disrupted sleep accelerates beta-amyloid accumulation in Alzheimer’s models.

The study coordinated by Vercelli and Granata shows that the molecule MR-409, developed in Miami, slows the progression of SMA.