EB is Associate Professor in Human Anatomy at the University of Turin since 2020. She completed her PhD in Neuroscience in 2010 with the supervision of Prof. Filippo Tempia (Lab. Neurophysiology of Neurodegenerative Diseases) and her postdoc with the supervision of Prof. Annalisa Buffo (Lab. Physiopathology of neural stem cells) at the University of Turin. Since 2017, EB has been leading her research unit on independent fundings (Cariplo Ricerca Biomedica Giovani Ricercatori, Italian Foundation Multiple Sclerosis (FISM), Cassa di Risparmio di Torino (CRT), Telethon Foundation, Italian Ministry of Research). EB’s research unit currently includes 2 PhD students (Martino Bonato and Maryam K. Ardakani) and 1 junior fellow (Niccolò Di Cintio).
Research focus
Since 2010, EB’s research has been focused on the mechanisms regulating oligodendrocyte biology and crosstalk with neurons in physiology and pathology. In the last 5 years, EB’s studies focused on:
1) Mechanisms underlying oligodendrocyte heterogeneity and dysfunctions in animal models of developmental disorders with dysmyelination (i.e. autosomal recessive primary microcephaly-17; doi: 10.1038/s41467-022-30010-6 and ongoing research).
2) how exposure to airborne pollution – and particularly to particulate matter (PM) – affects myelin repair and the disease course in the experimental autoimmune encephalomyelitis (EAE) mouse models of Multiple Sclerosis (doi: 10.1016/j.neuint.2021.104991 and ongoing research).
EB has a documented experience in in vivo (i.e. high-resolution histological analyses including myelin reflectance imaging, gene expression analyses, behavioral tests, models of dys-/de-myelination) and in vitro (i.e. primary glial cell cultures, myelination assays) studies.
