On going projects
Physiopathology of neural stem cells
Custom-made neuron for cell therapy in Parkinson’s and Huntington’s disease
ERC Synergy Grant 2024 | European Research Council
Role of interleukin 6 in the pathogenesis of Rett syndrome: focus on astrocyte-neuron crosstalk and its therapeutic implication
2023 – 2025 | PRIN-PNRR 2022 MUR Ministry of University and Research
Targeting glial cell dysfunctions to treat cognitive defects and epilepsy in primary autosomal recessive microcephaly-17 (MCPH17) models
2023 – 2025 | PRIN – MUR Ministry of University and Research
In vitro and in vivo molecular mapping of cell therapy for Huntington Disease at single-cell resolution
2023 – 2025 | PRIN – MUR Ministry of University and Research
Targeting oligodendroglial cell dysfunctions to treat cognitive defects and epilepsy in primary autosomal recessive microcephaly-17 (MCPH17) models
2023 – 2025 | Telethon Foundation
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Adult Neuroplasticity
Nr2f1-dependent regulation of Mitochondrial Function in Neural Development and Disease
2023-2026 | Bando PRIN 2022 – MUR PRIN Italian Ministry of University and Research
The role of miR-211 in neuronal aging: From Disease Mechanisms to Therapy
2023-2026 | Bando PRIN-PNRR 2022 – Italian Ministry of University and Research
Neurodevelopmental disorders: study of pathogenic mechanisms and identification of new potential therapeutic targets
2024-2027 | FONDAZIONE CRT
Discovering the Effectors of LIfestyle-driven Memory enhancement via InflammaTion – DELIMIT
2023-2026 | Bando PRIN-PNRR 2022 MUR Ministry of University and Research
Characterization and modulation of “immature” neurons: a potentially exploitable reservoir of non-newly generated cells involved in plasticity of the rodent and human cerebral cortex2023-2026 | Bando PRIN-2022 – Ministry of University and Research
2021-2025 | Bando “TRAPEZIO” – Fondazione Compagnia di San Paolo
Imprinted SCENTs: odour control of mate preference
2021-2025 | Bando “TRAPEZIO – Paving the way to research excellence and talent attraction” – Fondazione Compagnia di San Paolo
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Embryonic neurogenesis
IDH1/2 mutation inhibition in lower grade gliomas: from preclinical models to clinical applications
2024-2026 | Next Generation EU PNRR 2023
Dissection of common mechanisms in genetic primary microcephaly.
2023-2025 | Project PRIN 2022, funded by MIUR through the Next Generation EU program
Development of Citron Kinase as a therapeutic target for brain tumors.
2019-2024 | Italian Association for Cancer Research (AIRC)
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Brain development and disease
The involvement of the small heat shock protein HSPB8 in amyotrophic lateral sclerosis
2021-2025 | AFM Telethon
INNOVA: Italian network of excellence for advanced diagnosis
2021-2026 | PNRR Project
Lab-on-chip for a predictive and precision medicine in Neurocovid
2022-2024 | Bando INFRA-P Regione Piemonte
Uncovering the mechanism of action and synergistic potential of a SMA repositioned therapy
2022-2025 | SMA Europe
A combinatorial pharmacotherapeutic approach to counteract Spinal Muscular Atrophy
2022-2025 | AFM Telethon
Development and testing of new molecules for the experimental treatment of sarcopenia
2022-2025 | Flagship project INNDIANA, Spoke 5 “Industry for Health and Silver Economy”, Progetto PNRR NODES
Evaluation of the effect of leriglitazone on brain iron deposits in a murine model of Alzheimer’s disease
2023-2026 | Minoryx Therapeutics S.L.
D34Health: Digital Driven Diagnostics, prognostics and therapeutics for sustainable Health care
2023-2026 | Piano Nazionale per gli investimenti Complementari (PNC) MUR
MULTIMALZ: A multiscale imaging approach to study early alterations in an Alzheimer cerebral organoid
2024-2025 | Progetto Partenariato Esteso “MNESYS”, Spoke 2, Università degli Studi della Campania
Understanding and targeting Chemotherapy-related neurotoxicity
2024-2026 | MUR-Next Generation EU-PRIN2022
A 3D bioprinted spinal cord model to reach functional meaningful and clinically translatable regeneration
2024-2026 | MUR-Next Generation EU-PRIN2022
Targeting mACONITASE and KIF5A to rescue mitochondrial mobility and function for the treatment of motor neuron diseases
2024-2026 | MUR-Next Generation EU-PRIN2022
DAISI&RON: Degli Anziani In Salute con Intravides e Robot Nurse
2024-2026 | Iniziative di ricerca per tecnologie e percorsi innovativi in ambito Sanitario e Assistenziale Progetto PNC0000003 – Anthem – AdvaNced
REACT: Rebalancing the epitranscriptional landscape as an advanced therapy in SMA
2025-2026 | CURE SMA
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Neurophysiology of neurodegenerative diseases
Collaboration related to the link between the role of NURR1 in physiological and pathological conditions and the effects of various Immunic compounds.
2024-2026 | Immunic Therapeutics
Atassia Telangiectasia: identificazione di meccanismi di neurodegenerazione affrontabili con trattamenti farmacologici
2023-2025 | Fondazione CRT
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Aging and Alzheimer’s Disease
Hydroxytyrosol of olive oil: a promising bioactive compound to prevent hyperphosphorylation of tau protein in Alzheimer’sdisease
2024-2026 | Airalzh-Grants-for-Young-Researchers 2024
Neuroprotective role of the GHRH analog MR-409 in experimental models of Alzheimer’s disease
2023-2025 | BENEFICENTIA Stiftung Found
Study of early plasma markers of Alzheimer’sdisease: role of miRNA218
2024-2026 | CRT Foundation
Extracellular vesicles derived from preconditioned Mesenchymal stem cell: a new challenge for AD therapy?
2023-2026 | PRIN Ministry of University and Research
Selection and characterization of a new transgenic mouse model for the study of Alzheimer’s disease: 5xTg-AD/hTauTg
2023-2025 | Ricerca locale UNITO
The role of glymphatic system in sleep-dependent memory consolidation circuits
2023-2025 | Ricerca locale UNITO
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Neuroendocrinology
Phytoestrogens and hypoproteindiets in mothers with Anorexia Nervosa, whatalterations for neurodevelopment of offspring?
2024 – 2026 | Fondazione CRT
Developmental, Reproductive and Metabolic effects of Endocrine Disruptors: the DReaM-ED study
2022-2025 | PRIN Italian Ministry of University and ResearchE (2020)
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Neuropsychopharmacology
Diet and Health Project: Impact of the Ketogenic Diet in the Treatment of Drug-Resistant Epilepsy
2025-2027 | CRT Foundation
Matrix Metalloproteinase-9 and PeriNeuronal Nets: new therapeutic targets for Fragile X Syndrome
2023-2025 | PRIN Italian Ministry of University and Research
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Nerve Regeneration
Development of nano/micro-engineered devices for applications in peripheral nervous system pathological models (ENGInerve)
2023 – 2025 | PRIN Italian Ministry of University and Research
Gut and NeuroMuscular system: investigating the impact of microbiota on nerve regeneration and muscle reinnervation after peripheral nerve injury (Gut-NeuroMuscle)
2023 – 2025 | PRIN Italian Ministry of University and Research
New insights into myelin maintenance and peripheral nerve regeneration: the role of Beclin1 (INNER-BECN1)
2023 – 2025 | PRIN-PNRR 2022 Italian Ministry of University and Research
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