Physiopathology of neural stem cells
We are interested in understanding the mechanisms that regulate development and repair of the central nervous system.
Neurophysiology of neurodegenerative diseases
We study the deficits of electrical signals of nerve cells at the basis of some neurodegenerative and psychiatric disorders.
Brain development and disease
We study cellular and molecular mechanisms underlying neural development and neurodegeneration, to understand brain function and develop new therapeutic strategies.
Aging and Alzheimer’s Disease
Our group is engaged in studying the cellular and molecular mechanisms related to aging that cause Alzheimer’s disease, to contribute to the development of new therapies.
Clinical neurobiology
We study the immune-pathogenesis of multiple sclerosis and the responsivity of patients to pharmacological treatments, in order to develop new diagnostic tools.
Adult neurogenesis
Our research is focused on persistent neurogenesis in adult mammals. We study both neural stem cell niches and parenchymal neurogenesis in order to foster brain repair.
Neuropsychopharmacology
The focus of our research is delineating the neural circuitry underlying anxiety, stress response and mood at molecular and cellular levels.
Nerve regeneration
The focus of our research is the definition of innovative strategies of tissue engineering for improving peripheral nerve repair and regeneration.
Neuroendocrinology
Our goal is the study of the interactions among steroid hormones and the nervous system, their roles in the differentiation and plasticity of neural circuits.
Embryonic neurogenesis
We study the molecular mechanisms that control neuron generation, survival and differentiation during normal brain development and how their alteration may lead to neurodevelopmental disorders, such as microcephaly and Down syndrome.