Eur J Neuroscience, S. Bonzano

Eur J Neuroscience, September 2014

Odour enrichment increases adult-born dopaminergic neurons in the mouse olfactory bulb

Bonzano S ¹ , Bovetti S, Fasolo A, Peretto P, De Marchis S

Olfactory bulb (OB) dopaminergic neurons are key elements in odour processing. Here, we report that prolonged odour enrichment produces a selective increase of the dopaminergic (TH-positive) population in the OB glomerular layer. This effect is achieved by enhanced integration/survival of adult generated dopaminergic cells and allows dynamic changes in the OB glomerular circuits that could be critical to respond to the environmental incoming information [ read more ]

¹ Department of Life Sciences and Systems Biology, University of Torino, Italy; Neuroscience Institute Cavalieri Ottolenghi (NICO), Orbassano, Italy.