Marta Ribodino

Born in Saluzzo on 01.06.1996. Italian

Education
2021. Master’s Degree in Medical Biotechnology (summa cum laude), University of Turin, Italy
2018. Bachelor Degree in Biotechnology (summa cum laude), University of Turin, Italy

Current position
PhD student

Previous positions
2020-2021. Research Fellow, Department of Neuroscience Rita Levi Montalcini, University of Turin, PI: Prof. Annalisa Buffo
2017-2020. Undergraduate student, Department of Neuroscience Rita Levi Montalcini, University of Turin, PI: Prof. Annalisa Buffo

Main research interest
- Study of the neuroanatomical and functional integration of human striatal neurons into rodent models of Huntington Disease
- Study of the mechanisms underlying glial cell defects occurring in the Autosomal Dominant Leukodystrophies (ADLD) through the differentiation of both ADLD and non-diseased patient-derived human induced pluripotent stem cells into mature astrocytes and oligodendrocytes  
- Study of the astrocyte reactivity and the role of the astrocytic transcription factor SOX2 in the modulation of the inflammatory environment upon quinolinic acid (QA)-mediated excitotoxic lesion in mice

Expertise
Cell culture: hiPSC maintenance and glial differentiation, glial cell cultures.
Histology: perfusion, tissue fixation, cryostat and vibratome sectioning, immunofluorescence and immunohistochemistry. Molecular biology: RNA/DNA extraction, PCR, RT-PCR, oligonucleotide design.
Microscopy: brightfield, fluorescence, confocal, stereological counting, 3D reconstructions of light and confocal microscopy acquisitions.
Behavioral test.
Surgery: stereotaxic injections, cell transplantation. Transgenic mouse line breeding and BSL2 animal management.
Computer skills and statistical analysis, Inkscape, Photoshop.