Pubblicazioni

2023

Brigitta Bonaldo, Antonino Casile, Francesca Montarolo, Martina Bettarelli, Francesca Napoli, Stefano Gotti, GianCarlo Panzica, Marilena Marraudino (2023) Effects of perinatalexposure to bisphenol A or S in EAE model of multiple sclerosis. Cell and Tissue Research. 

2022

B. Bonaldo, L. Gioiosa, GC. Panzica, M. Marraudino (2022) Exposure to either bisphenol A or S represents a risk for crucial behaviors for pup survival, such as spontaneous maternal behavior in mice. Neuroendocrinology. https://doi.org/10.1159/000526074 

Marraudino M, Bonaldo B, Vitiello B, Bergui GC, Panzica G. (2022) Sexual Differences in Internet Gaming Disorder (IGD): From Psychological Features to Neuroanatomical Networks J Clin Med. 2022 Feb 16;11(4):1018. doi: 10.3390/jcm11041018.

Panzica G, Melcangi RC. Neuroactive steroids: From basic research to clinical use (2022) J Neuroendocrinol. Feb;34(2):e13102. doi: 10.1111/jne.13102.

Grassi D, Marraudino M, Garcia-Segura LM, Panzica GC (2022) The hypothalamic paraventricular nucleus as a central hub for the estrogenic modulation of neuroendocrine function and behavior Front Neuroendocrinol. Jan 5;65:100974. doi: 10.1016/j.yfrne.2021.100974.

2021

Aspesi D, Farinetti A, Marraudino M, Morgan GSK, Marzola E, Abbate-Daga G, Gotti S (2021) Maternal separation alters the reward system of activity-based anorexia rats. Psychoneuroendocrinology. Nov;133:105393. doi: 10.1016/j.psyneuen.2021.105393.

Perga S, Montarolo F, Martire S, Bonaldo B, Bono G, Bertolo J, Magliozzi R, Bertolotto A.(2021) Overexpression of the ubiquitin-editing enzyme A20 in the brain lesions of Multiple Sclerosis patients: moving from systemic to central nervous system inflammation. Brain Pathol. Mar;31(2):283-296. doi: 10.1111/bpa.12906. Epub 2020 Nov 18. PMID: 33051914

Bonaldo B., Casile A., Bettarelli M., GottiS., Panzica G., Marraudino M. (2021) Effects of chronic exposure to bisphenol A in adult female mice on social behavior, vasopressin system, and estrogen membrane receptor (GPER1). European Journal of Histochemistry 65(s1):3272. doi: 10.4081/ejh.2021.3272.

Marilena Marraudino, Giovanna Ponti, Chantal Moussu, Alice Farinetti, Elisabetta Macchi, Paolo Accornero, Stefano Gotti, Paloma Collado, Matthieu Keller, Giancarlo Panzica (2021) Early Postnatal Genistein Administration Affects Mice Metabolism and Reproductionin a Sexually Dimorphic Way. Metabolites11, 449. DOI: 10.3390/metabo11070449

Marraudino M, Bo E, Carlini E, Farinetti A, Ponti G, Zanella I, Di Lorenzo D, Panzica GC, Gotti S. Hypothalamic Expression of Neuropeptide Y (NPY) and Pro-OpioMelanoCortin (POMC) in Adult Male Mice Is Affected by Chronic Exposure to Endocrine Disruptors. Metabolites. 2021 Jun 9;11(6):368. doi: 10.3390/metabo11060368. PMID: 34207679; PMCID: PMC8228876.

Collantoni E, Tenconi E, Solmi M, Meneguzzo P, Marzola E, D'Agata F, Gotti S, Daga GA, Manara R, Favaro A. Hippocampal volumes in anorexia nervosa at different stages of the disorder. Eur Eat Disord Rev. 2021 Jan;29(1):112-122. doi: 10.1002/erv.2806. Epub 2020 Nov 13. PMID: 33186479.

2020

Llorente R, Marraudino M, Carrillo B, Bonaldo B, Simon-Areces J, Abellanas-Pérez P, Rivero-Aguilar M, Fernandez-Garcia JM, Pinos H, Garcia-Segura LM, Collado P, Grassi D (2020) G Protein-Coupled Estrogen Receptor Immunoreactivity Fluctuates During the Estrous Cycle and Show Sex Differences in the Amygdala and Dorsal Hippocampus.  Front Endocrinol (Lausanne). 2020 Aug 7;11:537. doi: 10.3389/fendo.2020.00537.

Marraudino M, Carrillo B, Bonaldo B, Llorente R, Campioli E, Garate I, Pinos H, Garcia-Segura LM, Collado P, Grassi D (2020) G protein-couple destrogen receptor immunoreactivity in the rat hypothalamus is widely distributed in neurons, astrocytes and oligodendrocytes, fluctuates during the estrouscycle and is sexually dimorphic. Neuroendocrinology. 2020 Jun 22. DOI 10.1159/000509583.

Panzica G., Melacangi R.C. (guest editors) Steroids and Nervous System (special issue) J. Neuroendocrinology 32 (1).

Panzica GC, Michetti F, Tayebati SK, De Giorgio R, Mariotti R, Pacini A, Quartu M 2020 A bridge among history and new multidisciplinary approaches: the role of G.I.S.N. in the field of neuromorphology. European Journal of Histochemistry 64, suppl.3: 1 https://doi.org/10.4081/ejh.2020.3200

Briguglio M, Vitale JA, Galentino R, Banfi G, Zanaboni Dina C, Bona A, Panzica GC, Porta M, Dell'Osso B, Glick ID. 2020 Healthy Eating, Physical Activity, and Sleep Hygiene (HEPAS) as the Winning Triad for Sustaining Physical and Mental Health in Patients at Risk for or with Neuropsychiatric Disorders: Considerations for Clinical Practice. Neuropsychiatr Dis Treat. Jan 8;16:55-70. doi: 10.2147/NDT.S229206.

Farinetti A, Aspesi D, Marraudino M, Marzola E, Amianto F, Abbate-Daga G, Gotti S. 2020a Sexually dimorphic behavioral effects of maternal separation in anorexic rats. Dev Psychobiol. Apr;62(3):297-309. doi: 10.1002/dev.21909.

Farinetti A, Aspesi D, Marraudino M, Marzola E, Abbate-Daga G, Gotti S. 2020 Maternal Separation in ABA Rats Promotes Cell Proliferation in the Dentate Gyrus of the Hippocampus. Neuroscience. Oct 15;446:238-248. doi: 10.1016/j.neuroscience. 2020.08.005.

Collantoni E, Tenconi E, Solmi M, Meneguzzo P, Marzola E, D'Agata F, Gotti S, Daga GA, Manara R, Favaro A. 2020 Hippocampal volumes in anorexia nervosa at different stages of the disorder. Eur Eat Disord Rev. Nov 13. doi: 10.1002/erv.2806.

2019

Ruiz-Pino F, Miceli D, Franssen D, Vazquez MJ, Farinetti A, Castellano JM,Panzica G, Tena-Sempere M. Environmentally Relevant Perinatal Exposures toBisphenol A Disrupt Postnatal Kiss1/NKB Neuronal Maturation and Puberty Onset in Female Mice. Environ Health Perspect. 2019 Oct;127(10):107011. doi:10.1289/EHP5570. Epub 2019 Oct 25. PubMed PMID: 31652106.

Ponti G, Farinetti A, Marraudino M, Panzica G, Gotti S. Postnatal genisteinadministration selectively abolishes sexual dimorphism in specific hypothalamicdopaminergic system in mice. Brain Res. 2019 Dec 1;1724:146434. doi:10.1016/j.brainres.2019.146434. Epub 2019 Sep 3. PubMed PMID: 31491419.

Marraudino M, Farinetti A, Arevalo MA, Gotti S, Panzica G, Garcia-Segura LM. Sexually Dimorphic Effect of Genistein on Hypothalamic Neuronal Differentiationin Vitro. Int J Mol Sci. 2019 May 18;20(10). pii: E2465. doi:10.3390/ijms20102465. PubMed PMID: 31109056; PubMed Central PMCID: PMC6567056.

Nuzzi R, Scalabrin S, Becco A, Panzica G. Sex Hormones and Optic NerveDisorders: A Review. Front Neurosci. 2019 Feb 11;13:57. doi:10.3389/fnins.2019.00057. eCollection 2019. Review. PubMed PMID: 30804741; PubMedCentral PMCID: PMC6378504. 

Lagunas N, Marraudino M, de Amorim M, Pinos H, Collado P, Panzica G,Garcia-Segura LM, Grassi D. Estrogen receptor beta and G protein-coupled estrogenreceptor 1 are involved in the acute estrogenic regulation ofarginine-vasopressin immunoreactive levels in the supraoptic and paraventricular hypothalamic nuclei of female rats. Brain Res. 2019 Jun 1;1712:93-100. doi:10.1016/j.brainres.2019.02.002. Epub 2019 Feb 4. PubMed PMID: 30731078.

Marraudino M, Bonaldo B, Farinetti A, Panzica G, Ponti G, Gotti S. Metabolism Disrupting Chemicals and Alteration of Neuroendocrine Circuits Controlling FoodIntake and Energy Metabolism. Front Endocrinol (Lausanne). 2019 Jan 9;9:766. doi:10.3389/fendo.2018.00766. eCollection 2018. Review. PubMed PMID: 30687229; PubMedCentral PMCID: PMC6333703.

Montarolo F, Perga S, Martire S, Brescia F, Caldano M, Lo Re M, Panzica G,Bertolotto A. Study of the NR4A family gene expression in patients with multiple sclerosis treated with Fingolimod. Eur J Neurol. 2019 Apr;26(4):667-672. doi:10.1111/ene.13875. Epub 2018 Dec 22. PubMed PMID: 30565812.

Farinetti A, Aspesi D, Marraudino M, Marzola E, Amianto F, Abbate-Daga G, Gotti S. Sexually dimorphic behavioral effects of maternal separation in anorexic rats. Dev Psychobiol. 2019 Sep 9. doi: 10.1002/dev.21909. [Epub ahead of print] PubMed PMID: 31502241.

2018

Farinetti A, Marraudino M, Ponti G, Panzica GC, Gotti S (2018) Chronic treatment with tributyltin induces sexually dimorphic alterations in the hypothalamic POMC system of adult mice. Cell Tissue Research 2018 Aug 4. doi: 10.1007/s00441-018-2896-9.

Briguglio M, Dell’Osso B, Panzica G, Malgaroli A, Banfi G, Zanaboni Dina C, Galentino R, Porta M (2018) Dietary Neurotransmitters: A Narrative Review on Current Knowledge. Nutrients. 10(5), 59. DOI 10.3390/nu10050591

Giatti S, Diviccaro S, Panzica G, Melcangi RC (2018) Post-finasteride syndrome and post-SSRI sexual dysfunction: two sides of the same coin? Endocrine. Apr 19. DOI 10.1007/s12020-018-1593-5.

Tetel MJ, de Vries GJ, Melcangi RC, Panzica G, O'Mahony SM (2018) Steroids, stress and the gut microbiome-brain axis. Journal of Neuroendocrinology. 30(2). Feb. DOI 10.1111/jne.12548.

Ponti G, Farinetti A, Marraudino M, Panzica G, Gotti S (2018) Sex Steroids and Adult Neurogenesis in the Ventricular-Subventricular Zone. Frontiers in Endocrinology 9:156. April. DOI10.3389/fendo.2018.00156

Marraudino M, Martini M, Trova S, Farinetti A, Ponti G, Gotti S, Panzica G (2018) Kisspeptin system in ovariectomized mice: estradiol and progesterone regulation. Brain Res. 2018, 1668: 8-14. doi:10.1016/j.brainres.2018.03.014. PubMed PMID: 29555237

Nuzzi R, Scalabrin S, Becco A, Panzica G. Gonadal Hormones and Retinal Disorders: A Review. Front Endocrinol (Lausanne). 2018, 9:66. (open access) doi: 10.3389/fendo.2018.00066. PubMed PMID: 29551993

Perga S, Martire S, Montarolo F, Giordani I, Spadaro M, Bono G, Corvisieri S, Messuti I, Panzica G, Orlandi F, Bertolotto A. The Footprints of Poly-Autoimmunity: Evidence for Common Biological Factors Involved in Multiple Sclerosis and Hashimoto's Thyroiditis. Front Immunol. 2018, 9:311. (open access) doi:10.3389/fimmu.2018.00311. PubMed PMID: 29527211

Panzica GC, Melcangi RC. New perspectives for the action of steroids in the brain. J Neuroendocrinol. 2018, 30(2) e12576. doi: 10.1111/jne.12576. PubMed PMID: 29385631.

Melcangi RC, Panzica GC. Neuroactive steroids and metabolic axis. Front Neuroendocrinol. 2018, 48:1-2. (open access) doi: 10.1016/j.yfrne.2017.11.002. PubMed PMID: 29146109.

Tetel MJ, de Vries GJ, Melcangi RC, Panzica G, O'Mahony SM. Steroids, stress and the gut microbiome-brain axis. J Neuroendocrinol. 2018, 30(2) e12548 (open access) doi:10.1111/jne.12548. PubMed PMID: 29024170.

Maria Elisabeth Street, Sabrina Angelini, Sergio Bernasconi, Ernesto Burgio, Alessandra Cassio, Cecilia Catellani, Francesca Cirillo, Annalisa Deodati, Enrica Fabbrizi, Vassilios Fanos, Giancarlo Gargano, Enzo Grossi, Lorenzo Iughetti, Pietro Lazzeroni, Alberto Mantovani, Lucia Migliore, Paola Palanza, Giancarlo Panzica, Anna Maria Papini, Stefano Parmigiani, Barbara Predieri, Chiara Sartori, Gabriele Tridenti, Sergio Amarri (2018). Current Knowledge on Endocrine Disrupting Chemicals (EDCs) from Animal Biology to Humans, from Pregnancy to Adulthood: Highlights from a National Italian Meeting. International journal of molecular sciences 19: 6 (1-44).

Marcinnò A, Marnetto F, Valentino P, Martire S, Balbo A, Drago A, Leto M, Capobianco M, Panzica G, Bertolotto A. (2018) Rituximab-induced hypogammaglobulinemia in patients with neuromyelitis optica spectrum disorders. Neurol Neuroimmunol Neuroinflamm. 2018 Sep 13;5(6):e498. doi: 10.1212/NXI.0000000000000498.

2017

Marraudino M, Miceli D, Farinetti A, Ponti G, Panzica G, Gotti S. Kisspeptin innervation of the hypothalamic paraventricular nucleus: sexual dimorphism and effect of estrous cycle in female mice. J Anat. 2017 Jun, 230(6):775-786. doi:10.1111/joa.12603. PubMed PMID: 28295274.

Heindel JJ, Blumberg B, Cave M, Machtinger R, Mantovani A, Mendez MA, Nadal A, Palanza P, Panzica G, Sargis R, Vandenberg LN, Vom Saal F. Metabolism disrupting chemicals and metabolic disorders. Reprod Toxicol. 2017, 68:3-33. (open access) - doi:10.1016/j.reprotox.2016.10.001. PubMed PMID: 27760374

G. Ponti, A. Rodriguez-Gomez, A. Farinetti, M. Marraudino, F. Filice, B. Foglio, G. Sciacca, G.C. Panzica, S. Gotti Early postnatal genistein administration permanently affects nitrergic and vasopressinergic systems in a sex-specific way.  Neuroscience, Volume 346, 27 March 2017, Pages 203–215

Grassi D., Lagunas N., Pinos H., Panzica G.C., Garcia-Segura L.M., Collado P. NADPH-Diaphorase Colocalizes with GPER and Is Modulated by the GPER Agonist G1 in the Supraoptic and Paraventricular Nuclei of Ovariectomized Female Rats. Neuroendocrinology 2017;104:94-104
(DOI:10.1159/000445190)

Romano F, Perotto S, Cricenti L, Gotti S, Aimetti M. (2017) Epithelial Inclusions Following a Bilaminar Root Coverage Procedure with a Subepithelial Connective Tissue Graft: A Histologic and Clinical Study. Int J Periodontics Restorative Dent. Sep/Oct;37(5):e245-e252.

Perotto S, Romano F, Cricenti L, Gotti S, Aimetti M. (2017) Vascularization and Innervation of Connective Tissue Grafts in the Treatment of Gingival Recessions: A Histologic and Immunohistochemical Study. Int J Periodontics Restorative Dent. Jul/Aug;37(4):551-558.

Oboti L, Trova S, Schellino R, Marraudino M, Harris NR, Abiona OM, Stampar M, Lin W, Peretto P. (2017) Activity Dependent Modulation of Granule Cell Survival in the Accessory Olfactory Bulb at Puberty. Front Neuroanat. 2017 May 23;11:44.

2016

Schellino R, Trova S, Cimino I, Farinetti A, Jongbloets BC, Pasterkamp RJ, Panzica G, Giacobini P, De Marchis S, Peretto P.  Opposite-sex attraction in male mice requires testosterone dependent regulation of adult olfactory bulb neurogenesis. Scientific Reports, October 2016

Heindel JJ, Blumberg B, Cave M, Machtinger R, Mantovani A, Mendez MA, Nadal A, Palanza P, Panzica G, Sargis R, Vandenberg LN, Vom Saal F. Metabolism disrupting chemicals and metabolic disorders. Reprod Toxicol. 2016 Oct 17. pii: S0890-6238(16)30363-X. doi: 10.1016/j.reprotox.2016.10.001. [Epub ahead of print]

Kortenkamp A, Bourguignon JP, Slama R, Bergman Å, Demeneix B, Ivell R, Panzica G, Trasande L, Zoeller RT. EU regulation of endocrine disruptors: a missed opportunity. Lancet Diabetes Endocrinol. 2016 Aug;4(8):649-50. doi: 10.1016/S2213-8587(16)30151-6. No abstract available.

Bourguignon JP, Slama R, Bergman Å, Demeneix B, Ivell R, Kortenkamp A, Panzica G, Trasande L, Zoeller RT. Science-based regulation of endocrine disrupting chemicals in Europe: which approach? Lancet Diabetes Endocrinol. 2016 Aug;4(8):643-6. doi: 10.1016/S2213-8587(16)30121-8. No abstract available.

Bo E, Farinetti A, Marraudino M, Sterchele D, Eva C, Gotti S, Panzica G. Adult exposure to tributyltin affects hypothalamic neuropeptide Y, Y1 receptor distribution, and circulating leptin in mice.  Andrology. 2016 Jul;4(4):723-34. doi: 10.1111/andr.12222.

Melcangi RC, Panzica GC. Gender influence on neurodegenerative and psychiatric disorders. Neurosci Biobehav Rev. 2016 Aug;67:1. doi: 10.1016/j.neubiorev.2016.04.016. No abstract available.

Panzica G, Melcangi RC. Structural and molecular brain sexual differences: A tool to understand sex differences in health and disease. Neurosci Biobehav Rev. 2016 Aug;67:2-8. doi: 10.1016/j.neubiorev.2016.04.017. Review.

Slama R, Bourguignon JP, Demeneix B, Ivell R, Panzica G, Kortenkamp A, Zoeller RT. Scientific Issues Relevant to Setting Regulatory Criteria to Identify Endocrine-Disrupting Substances in the European Union. Environ Health Perspect. 2016 Oct;124(10):1497-1503.

Melcangi RC, Panzica G Editorial. J Steroid Biochem Mol Biol. 2016 Jun;160:1. doi: 10.1016/j.jsbmb.2016.03.001. No abstract available.

Porcu, P., Barron, A. M., Frye, C. A., Walf, A. A., Yang, S.-Y., He, X.-Y., Morrow, A. L., Panzica, G. C. and Melcangi, R. C. (2016), Neurosteroidogenesis today: novel targets for neuroactive steroid synthesis and action and their relevance for translational research. Journal of Neuroendocrinology, 28: n/a. doi: 10.1111/jne.12351

Giatti S., Foglio B., Romano S., Pesaresi M., Panzica G.C., Garcia-Segura L.M., Caruso D., Melcangi R.C. (2016) Effects of subchronic finasteride treatment and withdrawal on neuroactive steroid levels and their receptors in the male rat brain. Neuroendocrinology, 103: 746-757

Mele P., Zammaretti F., Longo A. Panzica G.C., Oberto A., Eva C. Sex-dependent regulation of hypothalamic neuropeptide Y- Y1 receptor gene expression in leptin treated obese (ob/ob) or lean mice. Brain Research, 1649:102-109

2015

Heindel JJ, vom Saal FS, Blumberg B, Bovolin P, Calamandrei G, Ceresini G, Cohn BA, Fabbri E, Gioiosa L, Kassotis C, Legler J, La Merrill M, Rizzir L, Machtinger R, Mantovani A, Mendez MA, Montanini L, Molteni L, Nagel SC, Parmigiani S, Panzica G, Paterlini S, Pomatto V, Ruzzin J, Sartor G, Schug TT, Street ME, Suvorov A, Volpi R, Zoeller RT, Palanza P. (2015) Parma consensus statement on metabolic disruptors. Environ Health. Jun 20;14:54. doi: 10.1186/s12940-015-0042-7

Farinetti A, Tomasi S, Foglio B, Ferraris A, Ponti G, Gotti S, Peretto P, Panzica GC. (2015) Testosterone and estradiol differentially affect cell proliferation in the subventricular zone of young adult gonadectomized male and female rats. Neuroscience. Feb 12;286:162-70. doi: 10.1016/j.neuroscience.2014.11.050

Bonomi M, Cappa M, Cariboni A, Di Schiavi E, Fabbri A, Ferlin A, Foresta C, Ghizzoni L, Jannini E, Krausz C, Loche S, Lombardo F, Maggi M, Maggi R, Maghnie M, Mancini A, Merlo G, Panzica G, Radetti G, Russo G, Simoni M, Sinisi AA, Persani L. (2014) Kallmann's syndrome and normosmic isolated hypogonadotropic hypogonadism: two largely overlapping manifestations of one rare disorder. JEndocrinol Invest. 2014 May;37(5):499-500. doi: 10.1007/s40618-014-0063-z. Epub 2014 Apr 9