Fisiopatologia delle cellule staminali cerebrali

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Gruppo guidato da Annalisa Buffo

Fisiopatologia delle cellule staminali cerebrali
enrica boda

Enrica Boda

Assistant Professor RTD in Human Anatomy

Contacts:

Tel  + 39 011 6706615
Fax + 39 011 6705451
e-mail: enrica.boda@unito.it

Born in Turin, 08.05.1981 - Italian
Education
2010 PhD in Neuroscience, University of Turin, Italy
2005 Master’s degree in Neurobiology (summa cum laude and honourable mention), University of Turin, Italy

Current position
Assistant Professor in tenure track (RTD-B) in Human Anatomy (BIO/16). Has achieved  the National Academic Qualification (ASN) as Associate Professor in Human Anatomy (05/H1, 2017-2023)

Previous positions
2015-2017  Senior Post-doc Fellow (Assegnista di Ricerca). Independent fundings granted by Cariplo Foundation (Ricerca Biomedica condotta da Giovani Ricercatori). Department of Neuroscience Rita Levi Montalcini and Neuroscience Institute Cavalieri Ottolenghi (NICO), University of Turin, Italy.
Jun-Aug  2015  Visiting Scholar in Dr. Akiko Nishiyama’s laboratory, Department of Physiology and Neurobiology, University of Connecticut, Storrs, CT (USA).
2010-2014  Post-doc Fellow, Department of Neuroscience Rita Levi Montalcini and Neuroscience Institute Cavalieri Ottolenghi (NICO), University of Turin, Italy. PI: Prof. Annalisa Buffo
2005–2009   PhD student, Department of Neuroscience, University of Turin, Italy. PI: Prof. Filippo Tempia
2003–2005  Undergraduate student, Department of Human and Animal Biology, University of Turin, Italy. PI: Prof. Isabelle Perroteau.

Grants, Fellowships and Awards
2015-2018  Cariplo Ricerca Biomedica condotta da Giovani Ricercatori, two-years project granted by Cariplo Foundation, Milan, Italy. Characterization of a novel microRNA involved in myelination: a new potential pathogenetic mechanisms in multiple sclerosis (ID: 2014-1207)
2015  Postdoctoral Fellowship granted by Fondazione Umberto Veronesi, Milan, Italy. Targeting oligodendrocyte progenitor cell division mode to improve myelin repair in the aging CNS
2014  Postdoctoral fellowship granted by Fondazione Umberto Veronesi, Milan, Italy. Rejuvenating the brain: targeting neural stem/progenitor cell division mode to improve cognitive functions and repair abilities of the aging CNS.
2012-2013  Giuseppe Levi Postdoctoral fellowship, Accademia Nazionale dei Lincei, Rome, Italy. Oligodendrocyte progenitor self-renewal and differentiation: insights into symmetric and asymmetric divisions and possible implications in dysmyelination following peri-natal hypoxia.
2009-2010  Post-doc fellowship, Dept. of Neuroscience, University of Turin. PI: Dr. Annalisa Buffo
2005-2009  PhD fellowship granted by the CRT (Cassa di Risparmio di Torino) Foundation, Lagrange Project for the study of Complex Systems. Dept. of Neuroscience, University of Turin. PI: Prof. Filippo Tempia
2006  OPTIME Award 2005-2006 (The best graduate student at the Faculty of Biology, University of Turin) by Unione Industriale di Torino.
2005  Antonio Marzullo Award (The best undergraduate students in Cellular Biology), granted by University of Trieste, Italy

Scientific interests
Oligodendroglia-neurons cross-talk in health and disease. Myelination. De-/Dis-myelinating disorders. Molecular mechanisms involved in the regulation of the self-renewal and differentiation of neural progenitor cells (neural stem cells  and oligodendrocyte progenitor cells).

Scientific collaborations
Prof. Maria Pia Abbracchio, Dr. Davide Lecca (Dept. Pharmacological Sciences, University of Milan, Italy)
Dr. Claudia Verderio (Institute of Neuroscience, CNR, Milan, Italy)
Prof. Ferdinando di Cunto, Dr. Federico Bianchi (Dept. of Molecular Biotechnology and Health Science and NICO, University of Turin, Italy)
Dr. Andrea Marcantoni (Dept. of Drug Science and Technology, University of Turin, Italy)
Prof. Alessandro Vercelli (Dept. of Neuroscience and NICO, University of Turin)
Prof. Verdon Taylor, Dr. Chiara Rolando (Embriology and Stem Cell Biology, Dept. of Biomedicine, University of Basel, Basel, Switzerland)
Prof. Martin Schwab (University of Zurich, Zurich, Switzerland)
Dr. Anissa Kempf (Dept. of Physiology, Anatomy and Genetics, University of Oxford, UK)

Invited seminars and oral communications
Inherent heterogeneity in dorsal and ventral OPCs of the mouse CNS unveiled by Citron-kinase deletion. 3 December 2016, “More than Neurons Meeting: toward a less neuronocentric view of brain disorders”, Turin, Italy
Inherent heterogeneity in dorsal and ventral OPCs of the mouse CNS unveiled by Citron-kinase deletion. 23 November 2016, Convegno del Gruppo Italiano di Neuromorfologia (GISN), Verona, Italy
Heterogeneity and balance between proliferation and differentiation in the oligodendrocyte progenitor pool. 18 November 2015, Department of Pharmacological and Biomedical Sciences, University of Milan, Italy (“NICO meets DisFEB” Seminar Series: program of joint seminars organized by the Neuroscience Institute Cavalieri Ottolenghi, University of Turin and the Department of Pharmacological and Biomedical Sciences, University of Milan). Host: Prof. Roberto Melcangi
Balancing self-renewal and differentiation of the oligodendrocyte progenitor pool: insights into cell intrinsic regulatory mechanisms. 9 October 2015, SINS (Italian Society of Neuroscience) Meeting 2015, Cagliari, Italy
Heterogeneity and balance between proliferation and differentiation in the oligodendrocyte progenitor pool. 24 September 2015, XVI Congress of the Spanish Society of Neuroscience, Granada, Spain (in place of Dr. Annalisa Buffo)
Dynamics of self-renewal and differentiation of the oligodendrocyte progenitor pool in the CNS parenchyma. 29 November 2013, CNR, Institute of Neuroscience, Milan, Italy (invited by Dr. Patrizia Rosa)
The GPR17 receptor in oligodendroglial cells: focus on cell heterogeneity, maturation and participation in CNS damage. July 2012, Advanced School on New Approaches in Glial Cell Research, International Society for Neurochemistry, Barcelona, Spain (poster selected for oral presentation)
The GPR17 receptor in oligodendroglial cells: cell maturation, heterogeneity and participation in CNS damage. November 2011, IV Convegno Monotematico della SIF, ‘Immunità e infiammazione  nelle malattie del cervello. Nuovi bersagli farmacologici per terapie innovative’, Milan, Italy.
Guest referee for international scientific journals:
Neurochemical Research, Front Neurosci, Plos One, Purinergic Signalling, BMC Molecular Biology, Theriogenology
Reviewer in international grant projects:
2015  Ad-hoc reviewer for Multiple Sclerosis Research Australia

Scientific Societies
Italian Society of Neuroscience (SINS)
Italian Group for the Study of Neuromorphology (GISN)

News

Un nuovo interruttore per mettere in moto la plasticità cerebrale

In questo studio – pubblicato sulla prestigiosa rivista Developmental Cell - Annalisa Buffo ha contribuito con il suo gruppo di ricercatrici a identificare un nuovo recettore della proteina NoGo-A, un noto regolatore di tutte le forme di plasticità nervosa nel sistema nervoso centrale che studiamo ormai da vent'anni.

10 Ottobre 2017

Atassia: il training motorio preventivo rallenta la degenerazione neuronale

Lo studio delle nostre ricercatrici, pubblicato su Neurobiology of Disease, apre nuove prospettive per contrastare la morte neuronale nelle patologie neurodegenerative.

10 Marzo 2017

Scoperto un nuovo ruolo del ferro nella regolazione dell’ansia

Su Scientific Reports (gruppo Nature) di agosto uno studio delle nostre ricercatrici offre una nuova prospettiva sul ruolo del ferro nella regolazione delle funzioni fisiologiche cerebrali.

22 Agosto 2016