Fisiopatologia delle cellule staminali cerebrali

Condividi su

Gruppo guidato da Annalisa Buffo

Fisiopatologia delle cellule staminali cerebrali
valentina cerrato

Valentina Cerrato

PhD

Contacts:

Tel  + 39 011 6706632
Fax + 39 011 6705449
e-mail: valentina.cerrato@unito.it

Born in Turin on 21.07.1988 - Italian.
2007-2010 Interfaculty University School for Biotechnology , University of Turin
2010. Bachelor Degree in Biotechnology (110/110 cum laude).
2010 – 2012. Faculty of Medicine and Surgery, Master Degree Course in Medical Biotechnology, University of Turin.
2012. Master's Degree in Medical Biotechnology (110/110 cum laude and mention).
Thesis: "Identification and characterization of a peptide derived from equine lactadherin with antiviral activity against human Rotavirus" (Laboratory of molecular virology, supervised by Prof. David Lembo, Departmen of Clinical and Biological Sciences, University of Turin).

January 31st -  March 1st 2015
Training stay awarded by NENS Exchange Grant in the laboratory of Prof. Laura López-Mascaraque, Instituto Cajal, Madrid.

February, 2016. Route28 Summits in Neurobiology “Adult neurogenesis: form follows function and      function follows form”, DZNE (Deutsches Zentrum für Neurodegenerative Erkrankungen), Frauenchiemsee, Germany

May, 2017 International Training School “Reactive gliosis - from mechanobiology and signal transduction to molecular targets and disease pathogenesis”, University of Gothenburg,  Aspenäs Herrgård, Gothenburg, Sweden.

2014-2017.    PhD Student in Neuroscience, University of Turin. Research project about the role of glial cells during nervous system development and adulthood.
Tutor: Annalisa Buffo (Neuroscience Institute Cavalieri Ottolenghi, Department of Neuroscience Rita Levi Montalcini, University of Turin).

February 5th 2018.   PhD in Neuroscience. Thesis: “Astrogliogenesis in the cerebellum results from progenitors with distinct fate potencies and proliferative behaviors”. Tutor: Prof. Annalisa Buffo (Neuroscience Institute Cavalieri Ottolenghi, Department of  Neuroscience Rita Levi Montalcini, University of Turin).

October 2018 – Today. “Assegnista di ricerca”on the project “MiRNA125a dysregulation as a novel target to promote remyelination and understand pathogenetic mechanisms in multiple sclerosis”.

TEACHING EXPERIENCES

September 2017 – today. Didactic assistant (didattica integrativa) in Functioning of the human body Course - Physiology, Faculty of Nursing, University of Turin.

September 2017 – today. Didactic assistant (didattica integrativa) in Human Anatomy Course, Faculty of Nursing, University of Turin.

September 2017 – today. Tutor in Human Anatomy Course, Faculty of Scienze delle Attività Motorie e Sportive, University of Turin.

September 2017 – today. Mentorship of Chiara Ossola, master student in Neurobiology, University of Turin, Italy.

December 2016 – March 2018. Mentorship of Sara Lucisano, bachelor student in Biology, University of Piemonte Orientale, Alessandria, Italy.

September 2016 – July 2017. Mentorship of Chiara Ossola, bachelor student in Biotechnology, University of Turin, Italy.

June 2017. “Alternanza Scuola-lavoro”: 10-days- long stages for high school students (tutoring and laboratory activities, formulation and validation of scientific hypothesis, data collection, interpretation and discussion of results).

October 2015 – July 2016. Mentorship of Alessia Zotta, bachelor student in Biotechnology, University of Turin, Italy.

October 2014 – July 2016. Mentorship of Gabriele Liuzzi, master student in Biology, University of Turin, Italy.

June 2016. “Alternanza Scuola-lavoro”: 10-days- long stages for high school students (tutoring and laboratory activities, formulation and validation of scientific hypothesis, data collection, interpretation and discussion of results).

May 2015. Laboratory assistant/teacher for the Scientific Summer Academy, Fondazione Agnelli, May 26-29, Turin.

June 2014. Laboratory assistant/teacher for the Scientific Summer Academy, Fondazione Agnelli, June 9-13, Turin.

PERSONAL SKILLS AND EXPERTISE
During my doctoral training and, previously, as an undergraduate student, I acquired basic abilities in molecular biology (PCR, DNA isolation, transformation, plasmids purification, lentiviral vector production) and culture of both immortalized and primary lines of different CNS cell types (mainly astrocytes and neurospheres of neural stem cells). Moreover, I gained a deep expertise in the technique of in utero and postnatal electroporation in the mouse brain and a good dexterity in other in vivo procedures in mice, like injection of lentiviral vectors in utero (in the lateral and fourth ventricles) and early postnatally, cell transplantation experiments, perfusion and brain tissue collection. I also acquired extensive ability in histological and cytological procedures as well as in the use of bright-field, fluorescence and confocal microscopy. Beside that, I took advantage of novel in vivo clonal analysis techniques to investigate the fate potency of single precursors cells and trace their progenies.

POSTER AND ORAL PRESENTATIONS AT MEETINGS

POSTER: Cerrato Valentina, Parmigiani Elena, Leto Ketty, Gracia-Marques Jorge, Lòpez-Mascaraque Laura, Buffo Annalisa and Rossi Ferdinando "Origin and generation of different astroglial phenotypes in the cerebellum" FENS congress, Milan, July 5-9 2014.

POSTER:Cerrato Valentina, Parmigiani Elena, Leto Ketty, María Figueres-Oñate, Lòpez-Mascaraque Laura, and Buffo Annalisa "Origin and generation of different astroglial phenotypes in the cerebellum"  XII European Meeting on Glial Cells in Health and Disease, Bilbao, July 15-18 2015

POSTER:Cerrato Valentina, Parmigiani Elena, Leto Ketty, María Figueres-Oñate, Lòpez-Mascaraque Laura, and Buffo Annalisa "Origin and generation of different astroglial phenotypes in the cerebellum"  XVI Congress SINS, Cagliari, October 8-11 2015

ORAL PRESENTATION: Cerrato Valentina, Parmigiani Elena, María Figueres-Oñate, Fucà Elisa, Leto Ketty, Lòpez-Mascaraque Laura and Buffo Annalisa "Origin and development of astroglial heterogeneity in the cerebellum" 46th SfN annual meeting, San Diego (USA), 12-16 November 2016.

ORAL PRESENTATION: Cerrato Valentina, Parmigiani Elena, María Figueres-Oñate, Fucà Elisa, Leto Ketty, Lòpez-Mascaraque Laura and Buffo Annalisa "Astroglial heterogeneity in the cerebellum results from distinct embryonic and postnatal progenitors with different proliferative behaviors",  XXVI Congress G.I.S.N., Verona,  November 24-25 2016.

POSTER: Cerrato Valentina, Parmigiani Elena, María Figueres-Oñate, Fucà Elisa, Leto Ketty, Lòpez-Mascaraque Laura and Buffo Annalisa "Astroglial heterogeneity in the cerebellum results from distinct embryonic and postnatal progenitors with different proliferative behaviors",  MORE THAN NEURONS: towards a less neuronocentric view of brain disorders, Turin, 1-3 December 2016

POSTER: Cerrato Valentina, Parmigiani Elena, María Figueres-Oñate,, Aprato Jessica, De’sperati Claudio, Lòpez-Mascaraque Laura and Buffo Annalisa "Astroglial heterogeneity in the cerebellum results from distinct embryonic and postnatal progenitors with different proliferative behaviors",  International Training School “Reactive gliosis - from mechanobiology and signal transduction to molecular targets and disease pathogenesis”, Gothenburg, Sweden, 2-6 May 2017.

POSTER: Cerrato Valentina, Parmigiani Elena, María Figueres-Oñate,, Aprato Jessica, De’sperati Claudio, Lòpez-Mascaraque Laura and Buffo Annalisa "Astroglial heterogeneity in the cerebellum results from distinct embryonic and postnatal progenitors with different proliferative behaviors",  XIII European Meeting on Glial Cells in Health and Disease, Edimburgh, July 8-11 2017.

INVITED SEMINARS
“Cerebellar astroglial heterogeneity and role of Bergmann Glia during cerebellar foliation”, Instituto Cajal, Madrid (February 25th, 2015).

AWARDS AND SCHOLARSHIPS
2014. Awarded NENS Exchange Grant
2015. Awarded IBRO stipend for Introductory Course - Glia Meeting 2015
2016. One of the 45 students selected to attend the Route28 Summit in Neurobiology “Adult neurogenesis: form follows function and function follows form”, DZNE (Deutsches Zentrum für Neurodegenerative Erkrankungen), Frauenchiemsee, Germany.
September 15th, 2016. Price awarded for best poster presentation among the PhD Students in Neuroscience at D-Day 2016, organized by the Doctoral School in Life and Health Sciences, University of Turin.
November 25th, 2016. Price awarded as one of the best young oral presentations at the XXVI Congress G.I.S.N. , Verona,  November 24-25, 2016.
May 2017. Awarded COST Fellowship to attend the International Training School “Reactive gliosis – from mechanobiology and signal transduction to molecular targets and disease pathogenesis”, University of Gothenburg,  Aspenäs Herrgård, Gothenburg, Sweden.

> Curriculum Vitae

Publications:

>  PubMed.gov