Fisiopatologia delle cellule staminali cerebrali

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Gruppo guidato da Annalisa Buffo

Fisiopatologia delle cellule staminali cerebrali
valentina cerrato

Valentina Cerrato

Junior PostDoc

Contacts:

Tel  + 39 011 6706632
Fax + 39 011 6705449
e-mail: valentina.cerrato@unito.it

Born in Turin on 21.07.1988 - Italian.

Education
2018. PhD in Neuroscience cum laude, University of Turin, Italy
2012. Master’s Degree in Medical Biotechnology (summa cum laude and honorable mention), University of Turin, Italy
2010. Bachelor Degree in Biotechnology (summa cum laude), University of Turin, Italy

Current position
Young Post-doc fellow

Previous positions
2018 - up to now. Young Post-doc Fellow, Department of Neuroscience Rita Levi Montalcini and Neuroscience Institute Cavalieri Ottolenghi (NICO), University of Turin, Italy. PI: Prof. Annalisa Buffo
February 2015. Visiting Scholar in the laboratory of Prof. Laura López-Mascaraque, Instituto Cajal, Madrid.
2014-2017. PhD student, Department of Neuroscience, University of Turin, Italy. PI: Prof. Annalisa Buffo
2013. Post-lauream apprentice at the Neuroscience Institute Cavalieri Ottolenghi (NICO), Department of Neuroscience Rita Levi Montalcini, University of Turin, PI: Prof. Ferdinando Rossi.
2007–2012. Undergraduate student, Department of Clinical and Biological Sciences, University of Turin, Italy. PI: Prof. David Lembo.

Main research interest and expertise
My research focuses on the mechanisms of cerebellar development. Specifically, I am interested in elucidating the ontogenesis of glial heterogeneity in this brain region, through high throughput clonal and molecular analyses. In the past ten years of research activity in both the virology and neuroscience field, I acquired basic abilities in molecular biology (DNA and RNA isolation, PCR, qRT PCR, bacterial transformation, plasmids purification, lentiviral vector production) and culture of both immortalized and primary lines of different CNS cell types (mainly astrocytes and neurospheres of neural stem cells).

Moreover, I gained a deep expertise in the technique of in utero and postnatal electroporation in the mouse brain and a good dexterity in other in vivo surgical procedures in mice, like injection of lentiviral vectors in utero (in the lateral and fourth ventricles), early postnatally, and in adult animals, cell transplantation experiments, perfusion and brain tissue collection. I also acquired extensive ability in behavioral tests to assess both motor and anxiety-like behaviors in distinct mutant mouse lines. Moreover, I gained expertise in histological and cytological procedures as well as in the use of bright-field, fluorescence and confocal microscopy. Beside that, I took advantage of novel in vivo clonal analysis techniques to investigate the fate potency of single precursor cells and trace their progenies in the CNS.

Role in research
Responsible of research on astrocyte heterogeneity and cerebellar development; expert in clonal analyses

> Curriculum Vitae

Publications:

>  PubMed.gov

News

Come nasce una stella: origine e sviluppo degli astrociti, le vere 'star' del cervello

Svelato per la prima volta il processo che genera diversi tipi di astrociti nel cervello. Lo studio del nostro gruppo di ricerca guidato da Annalisa Buffo, pubblicato sulla prestigiosa rivista Plos Biology, conferma il ruolo cruciale degli astrociti nel corretto sviluppo e mantenimento della funzionalità neuronale, e apre nuove strade per comprendere i disturbi del neurosviluppo.

10 Ottobre 2018

Premio GiovedìScienza: Valentina Cerrato del NICO vince il Premio Elena Benaduce

Proclamati il 9 maggio al Salone del Libro i giovani ricercatori vincitori dell’VIII edizione del Premio GiovedìScienza, nato per incoraggiare i protagonisti della ricerca alla comunicazione della scienza. La competizione, organizzata da CentroScienza Onlus, è rivolta ai ricercatori under 35 di tutti gli enti di ricerca italiani. I 59 lavori iscritti quest’anno al premio, pervenuti da 11 regioni d’Italia, spaziano dalla fisica alla chimica passando per l’astrofisica; dalla psicologia alla geologia, alla nutrizione e ovviamente alle neuroscienze.

9 Maggio 2019