Neurogenesi embrionale

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Gruppo guidato da Ferdinando Di Cunto

Neurogenesi embrionale

Pubblicazioni

2018

Pallavicini G, Sgro F, Garello F, Falcone M, Bitonto V, Berto GE, Bianchi FT, Gai M, Chiotto AM, Filippi M, Cutrin JC, Ala U, Terreno E, Turco E and Di Cunto F. Inactivation of citron kinase inhibits medulloblastoma progression by inducing apoptosis and cell senescence. Cancer Res. 2018 Jun. doi: 10.1158/0008-5472.CAN-17-4060.

Dema A, Macaluso F, Sgrò F, Berto GE, Bianchi FT, Chiotto AA, Pallavicini G, Di Cunto F and Gai M. Citron kinase-dependent F-actin maintenance at midbody secondary ingression sites mediates abscission. J Cell Sci. 2018 Apr 2;131(8). doi: 10.1242/jcs.209080.

2017

Bianchi FT, Tocco C, Pallavicini G, Liu Y, Vernì F, Merigliano C, Bonaccorsi S, El-Assawy N, Priano L, Gai M, Berto GE, Chiotto AM, Sgrò F, Caramello A, Tasca L, Ala U, Neri F, Oliviero S, Mauro A, Geley S, Gatti M, Di Cunto F. Citron Kinase Deficiency Leads to Chromosomal Instability and TP53-Sensitive Microcephaly. Cell Rep. 2017 Feb 14;18(7):1674-1686. doi:10.1016/j.celrep.2017.01.054.

Gai M, Di Cunto F. Citron kinase in spindle orientation and primary microcephaly. Cell Cycle. 2017 Feb;16(3):245-246. doi:10.1080/15384101.2016.1252584.

2016

El Ghouzzi, V, Bianchi, F.T., Molineris, I., Mounce, B.C., Berto, G.E., Rak, M., Lebon, S., Aubry, L., Tocco, C., Gai, M., Chiotto, A.M., Sgro, F., Pallavicini, G., Simon-Loriere, E., Passemard, S., Vignuzzi, M., Gressens, P. and Di Cunto, F. (2016) ZIKA virus elicits P53 activation and genotoxic stress in human neural progenitors similar to mutations involved in severe forms of genetic microcephaly. Cell Death Dis, 7, e2440.

Gai, M., Bianchi, F.T., Vagnoni, C., Verni, F., Bonaccorsi, S., Pasquero, S., Berto, G.E., Sgro, F., Chiotto, A.M., Annaratone, L., Sapino, A., Bergo, A., Landsberger, N., Bond, J., Huttner, W.B. and Di Cunto, F. (2016) ASPM and CITK regulate spindle orientation by affecting the dynamics of astral microtubules. EMBO Rep, 17, 1396-1409.

Harding, B.N., Moccia, A., Drunat, S., Soukarieh, O., Tubeuf, H., Chitty, L.S., Verloes, A., Gressens, P., El Ghouzzi, V., Joriot, S., Di Cunto, F., Martins, A., Passemard, S. and Bielas, S.L. (2016) Mutations in Citron Kinase Cause Recessive Microlissencephaly with Multinucleated Neurons. Am J Hum Genet, 99, 511-520.

Sgro, F., Bianchi, F.T., Falcone, M., Pallavicini, G., Gai, M., Chiotto, A.M., Berto, G.E., Turco, E., Chang, Y.J., Huttner, W.B. and Di Cunto, F. (2016) Tissue-specific control of midbody microtubule stability by Citron kinase through modulation of TUBB3 phosphorylation. Cell Death Differ, 23, 801-813.

2015

Bergo, A., Strollo, M., Gai, M., Barbiero, I., Stefanelli, G., Sertic, S., Cobolli Gigli, C., Di Cunto, F., Kilstrup-Nielsen, C. and Landsberger, N. (2015) Methyl-CpG binding protein 2 (MeCP2) localizes at the centrosome and is required for proper mitotic spindle organization. J Biol Chem, 290, 3223-3237.

2014

Berto, G.E., Iobbi, C., Camera, P., Scarpa, E., Iampietro, C., Bianchi, F., Gai, M., Sgro, F., Cristofani, F., Gartner, A., Dotti, C.G. and Di Cunto, F. (2014) The DCR protein TTC3 affects differentiation and Golgi compactness in neurons through specific actin-regulating pathways. PLoS One, 9, e93721.

Molineris, I., Ala, U., Provero, P. and Di Cunto, F. (2014) Drug repositioning for orphan genetic diseases through Conserved Anticoexpressed Gene Clusters (CAGCs). BMC Bioinformatics, 14, 288.

Repetto, D., Camera, P., Melani, R., Morello, N., Russo, I., Calcagno, E., Tomasoni, R., Bianchi, F., Berto, G., Giustetto, M., Berardi, N., Pizzorusso, T., Matteoli, M., Di Stefano, P., Missler, M., Turco, E., Di Cunto, F. and Defilippi, P. (2014) p140Cap regulates memory and synaptic plasticity through Src-mediated and citron-N-mediated actin reorganization. J Neurosci, 34, 1542-1553.